Toxic Biological effects of the ingredients in Crest 3D White toothpaste when ingested during daily use: - Sodium fluoride: Causes dental fluorosis (tooth discoloration) and skeletal fluorosis (joint pain, bone thickening). Fluoride also affects thyroid functions and bone health. - Sodium lauryl sulfate (SLS): Causes skin and mucous membrane irritation leading to canker sores and dry mouth. - Sorbitol: In daily consumption causes gastrointestinal issues like bloating, gas, an