The Bill & Melinda Gates Foundation funded a project to develop a long-acting reversible contraceptive. It's a microneedle patch delivering a contraceptive hormone, aiming to provide women with a discreet, self-administered birth control option. The microneedle patch uses nanoparticles to encapsulate the contraceptive hormone, releasing it slowly. However, toxicities include nanoparticle accumulation in organs, oxidative stress, and inflammation. The payload in the nanotech b